The culmination of three decades of relentless dedication: RATIONALE Research represents our continued commitment to your skin health, ensuring our pioneering Formulations and Treatments continue to set a new benchmark in skincare excellence.
Research Paper 0: The Assessment of Skin Rejuvenation using Solar Protection and Solar Repair
Published Title: Long-Term Objective Assessments of Skin Rejuvenation Using Solar Protection and Solar Repair Shown Through Digital Facial Surface Analysis and Three-Dimensional Volumetric Assessment
Professor Yohei Tanaka, MDc
This paper assesses the impact our Formulations have on solar project and solar repair on this skin, specifically the Essential Six Signature Edition.
Research Paper 01: Examining the Impact of Solar Protection and Repair Skincare on Skin Health-Related Genes
Published Title: Up-Regulated Expression of ICAM1, PTG52, LCE3D, PPARD, and GM-CSF2 Following Solar Skincare Protection and Repair Strategies in a 3-Dimensional Reconstructed Human Skin Model.
Professor Yohei Tanaka, MD
This paper focuses on the 67 genes responsible for skin health. Richard Parker explains the impact the Essential Six Signature Edition were proven to have.
Research Paper 02: Facial Appearance Improvements and Gene Expression Changes with Topical Formulation for DNA Damage Repair
Published Title: In Vivo Improvements in Facial Appearanceand In Vitro Changes in Gene Expression Using a Topical Formulation Designed to Repair Environmentally Induced DNA Damage.
Amaryllis Aganahi, Richard Parker, Professor Yohei Tanaka, MD
This paper focuses on the nightly repair of sun damage and skin improvements using #6 The Night Crème.
Research Paper 03: Assessing the Photoprotective Ability of Coloured Iron Oxides in Tinted Sunscreens against Ultraviolet, Visible Light and Near-Infrared Radiation
Published Title: Novel Low Viscosity Zinc Oxide, Iron Oxides and Erioglaucine Sunscreen Potential to Protect from Ultraviolet, Visible Light and Near-Infrared Radiation.
Professor Yohei Tanaka MD, Richard Parker, Amaryllis Aganahi and Ailen Pedroso.
This Research Paper explores whether a combination of iron oxides,erioglaucine and zinc oxide is best to block light across the Solar spectrum.
Research Paper 04: An Analysis in the Changes of Gene Expression with SPF50+ Solar Protection after UV and Blue Light Exposure
Published Title: Gene Expression Change Analysis Following Specific Comprehensive Solar Protection SPF50+ after Ultraviolet Light and Blue Light Exposure in a 3Dimensional Reconstructed Human Skin Mode
Amaryllis Aganahi, Richard Parker, Professor Yohei Tanaka, MD
This Research Paper explores gene expression changes with SPF50+ solar protection after UV and blue light exposure.
Research Paper 07: A Novel Protection and Repair Skincare Regimen Shows Efficacy for Improving Environmental Skin Ageing
Published Title: A Novel Protection and Repair Skincare Regimen Shows Efficacy for Improving Environmental Skin Ageing
Dr. Patricia K. Farris, Dr. Zoe Diana Draelos, Dr. Yohei Tanaka, Dr. Vivian Bucay, Amaryllis Aganahi, and Natasha Ribeiro and Richard Parker
This 12-week study explores the efficacy of The Signature Essential Six ritual in mitigating the signs of environmental skin ageing.
